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Article

Multipoint linkage mapping using sibpairs: non-parametric estimation of trait effects with quantitative covariates.

Genetic epidemiology - 1 Jan 2005

Chiou Jeng-Min, Liang Kung-Yee, Chiu Yen-Feng

Abstract excerpt

Multipoint linkage analysis using sibpair designs remains a common approach to help investigators to narrow chromosomal regions for traits (either qualitative or quantitative) of interest. Despite its popularity, the success of this approach depends heavily on how issues such as genetic heterogeneity, gene-gene, and gene-environment interactions are properly handled. If addressed properly, the likelihood of...

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PMID: 15493060
DOI: 10.1002/gepi.20036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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