Model-Based Linkage Analysis of a Binary Trait.

Abstract excerpt

Linkage analysis is a statistical genetics method to localize disease and trait genes to specific chromosome regions. The analysis requires pedigrees with members who vary among each other in the trait of interest and who have been genotyped with known genetic markers. Linkage analysis tests whether any of the marker alleles cosegregate with the disease or trait within the pedigree. Evidence of cosegregation is...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chromosomes, Human
• Share to Genetic Linkage
• Share to Genetic Loci