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Article

Interpreting analyses of continuous covariates in affected sibling pair linkage studies.

Genetic epidemiology - 1 Sept 2007

Schmidt Silke, Qin Xuejun, Schmidt Michael A, Martin Eden R, Hauser Elizabeth R

Abstract excerpt

Datasets collected for linkage analyses of complex human diseases often include a number of clinical or environmental covariates. In this study, we evaluated the performance of three linkage analysis methods when the relationship between continuous covariates and disease risk or linkage heterogeneity was modeled in three different ways: (1) The covariate distribution is determined by a quantitative trait locus...

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PMID: 17410529
DOI: 10.1002/gepi.20227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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