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Article

Ordered subset analysis in genetic linkage mapping of complex traits.

Genetic epidemiology - 1 Jul 2004

Hauser Elizabeth R, Watanabe Richard M, Duren William L, Bass Meredyth P, Langefeld Carl D, Boehnke Michael

Abstract excerpt

Etiologic heterogeneity is a fundamental feature of complex disease etiology; genetic linkage analysis methods to map genes for complex traits that acknowledge the presence of genetic heterogeneity are likely to have greater power to identify subtle changes in complex biologic systems. We investigate the use of trait-related covariates to examine evidence for linkage in the presence of heterogeneity....

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Identifiers

PMID: 15185403
DOI: 10.1002/gepi.20000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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