Article
Multivariate and multilocus variance components method, based on structural relationships to assess quantitative trait linkage via SEGPATH.
Genetic epidemiology - 1 Feb 2003
Province M A, Rice T K, Borecki I B, Gu C, Kraja A, Rao D C
Abstract excerpt
A general-purpose modeling framework for performing path and segregation analysis jointly, called SEGPATH (Province and Rao [1995] Stat. Med. 7:185-198), has been extended to cover "model-free" robust, variance-components linkage analysis, based on identity-by-descent (IBD) sharing. These extended models can be used to analyze linkage to a single marker or to perform multipoint linkage analysis, with a single...
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