Multipoint affected sibpair linkage methods for localizing susceptibility genes of complex diseases.

doi:10.1002/gepi.10215

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Article

Multipoint affected sibpair linkage methods for localizing susceptibility genes of complex diseases.

Genetic epidemiology - 1 Feb 2003

Glidden David V, Liang Kung-Yee, Chiu Yen-Feng, Pulver Ann E

Abstract excerpt

Recently, Liang et al. ([2001] Hum. Hered. 51:64-78) proposed a general multipoint linkage method for estimating the chromosomal position of a putative susceptibility locus. Their technique is computationally simple and does not require specification of penetrance or a mode of inheritance. In com...

Topics

Age of Onset
Chromosome Mapping
Genetic Diseases, Inborn
Genetic Predisposition to Disease
Humans
Models, Genetic
Psychotic Disorders
Schizophrenia
Siblings

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