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Article

Multipoint affected sibpair linkage methods for localizing susceptibility genes of complex diseases.

Genetic epidemiology - 1 Feb 2003

Glidden David V, Liang Kung-Yee, Chiu Yen-Feng, Pulver Ann E

Abstract excerpt

Recently, Liang et al. ([2001] Hum. Hered. 51:64-78) proposed a general multipoint linkage method for estimating the chromosomal position of a putative susceptibility locus. Their technique is computationally simple and does not require specification of penetrance or a mode of inheritance. In complex genetic diseases, covariate data may be available which reflect etiologic or locus heterogeneity. We developed...

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PMID: 12548672
DOI: 10.1002/gepi.10215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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