Article
Identity-by-descent estimation and mapping of qualitative traits in large, complex pedigrees.
Genetics - 1 Jul 2008
Abney Mark
Abstract excerpt
Computing identity-by-descent sharing between individuals connected through a large, complex pedigree is a computationally demanding task that often cannot be done using exact methods. What I present here is a rapid computational method for estimating, in large complex pedigrees, the probability that pairs of alleles are IBD given the single-point genotype data at that marker for all individuals. The method can...
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