Article
A statistical method for identification of polymorphisms that explain a linkage result.
American journal of human genetics - 1 Feb 2002
Sun Lei, Cox Nancy J, McPeek Mary Sara
Abstract excerpt
Suppose that many polymorphic sites have been identified and genotyped in a region showing strong linkage with a trait. A key question of interest is which site (or combination of sites) in the region influences susceptibility to the trait. We have developed a novel statistical approach to this problem, in the context of qualitative-trait mapping, in which we use linkage data to identify the polymorphic sites...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
