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Studies on the HPRT mutant frequency in T lymphocytes from healthy Indian male population as a function of age and smoking.

Mutation research - 22 Nov 2004

Kumar P R Vivek, Hamza V Zareena, Mohankumar Mary N, Jeevanram R K

Abstract excerpt

Mutant frequency at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene in the peripheral blood lymphocytes obtained from 44 healthy individuals (23 non-smokers and 21 smokers) of an Indian male population was studied using T-lymphocyte cloning assay. It was found that lnMF increased with age at a rate of 2.5% per year (P <0.001). Blood samples from smokers showed a significant (P <0.037) increase in...

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Identifiers

PMID: 15491638
DOI: 10.1016/j.mrfmmm.2004.07.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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