Measurement of HPRT mutant frequencies in T-lymphocytes from healthy human populations.

doi:10.1016/0027-5107(93)90115-v

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Article

Measurement of HPRT mutant frequencies in T-lymphocytes from healthy human populations.

Mutation research - 1 Feb 1993

Branda R F, Sullivan L M, O'Neill J P, Falta M T, Nicklas J A, Hirsch B, Vacek P M, Albertini R J

Abstract excerpt

Somatic cell mutant frequencies at the hprt locus of the X-chromosome were measured with the T-lymphocyte cloning technique in healthy human populations. A statistical analysis was performed of assays from 232 individuals (77 males and 155 females) ranging in age from 19 to 80 years. Data from 4...

Topics

Adult
Age Factors
Aged
Aged, 80 and over
Clone Cells
Female
Humans
Hypoxanthine Phosphoribosyltransferase
Male
Middle Aged
Mutation
Sex Factors
Smoking
Statistics as Topic
T-Lymphocytes
Twins, Dizygotic

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