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Article

Measurement of HPRT mutant frequencies in T-lymphocytes from healthy human populations.

Mutation research - 1 Feb 1993

Branda R F, Sullivan L M, O'Neill J P, Falta M T, Nicklas J A, Hirsch B, Vacek P M, Albertini R J

Abstract excerpt

Somatic cell mutant frequencies at the hprt locus of the X-chromosome were measured with the T-lymphocyte cloning technique in healthy human populations. A statistical analysis was performed of assays from 232 individuals (77 males and 155 females) ranging in age from 19 to 80 years. Data from 4 donor groups were compiled: (a) 132 participants in a study of identical and fraternal twins; (b) 17 health care...

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Identifiers

PMID: 7678900
DOI: 10.1016/0027-5107(93)90115-v

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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