Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The influence of smoking and diet on the hypoxanthine phosphoribosyltransferase (hprt) mutant frequency in circulating T lymphocytes from a normal human population.

Mutation research - 1 Sept 1995

Duthie S J, Ross M, Collins A R

Abstract excerpt

The influence of the dietary antioxidants vitamin C, alpha- and beta-carotene, lycopene, lutein/zeaxanthin, phytofluene, beta-cryptoxanthin, retinol and alpha- and gamma-tocopherol on the hypoxanthine phosphoribosyltransferase (hprt) mutant frequency in human peripheral T lymphocytes was investigated. Twenty-five male non-smokers and 27 male smokers in the age range 50-59 years were recruited. Smokers showed a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidants
Share to Ascorbic Acid
Share to Diet

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypoxanthine Phosphoribosyltransferase

Share to Mutation

Share to Smoking

Share to T-Lymphocytes

Source

Identifiers

PMID: 7666869
DOI: 10.1016/0027-5107(95)00051-j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The influence of smoking and diet on the hypoxanthine phosphoribosyltransferase (hprt) mutant frequency in circulating T lymphocytes from a normal human population.PMID 7666869Read ↗

Factors affecting HPRT mutant frequency in T-lymphocytes of smokers and nonsmokers.Semantic proximity Read ↗

Dietary fruit and vegetables protect against somatic mutation in vivo, but low or high intake of carotenoids does not.Semantic proximity Read ↗

Enhanced hprt mutant frequency but no significant difference in mutation spectrum between a smoking and a non-smoking human population.Semantic proximity Read ↗

Mutational spectra at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in T-lymphocytes of nonsmoking and smoking lung cancer patients.Semantic proximity Read ↗

Influence of smoking and donor age on the spectrum of in vivo mutation at the HPRT-locus in T lymphocytes of healthy adults.Semantic proximity Read ↗

Impact of age and environment on somatic mutation at the hprt gene of T lymphocytes in humans.Semantic proximity Read ↗

Studies on the HPRT mutant frequency in T lymphocytes from healthy Indian male population as a function of age and smoking.Semantic proximity Read ↗

Frequencies of hprt mutant lymphocytes in smokers, non-smokers, and former smokers.Semantic proximity Read ↗

Influence of sex, smoking and age on human hprt mutation frequencies and spectra.Semantic proximity Read ↗

Spectrum of somatic mutation at the hypoxanthine phosphoribosyltransferase (hprt) gene of healthy people.Semantic proximity Read ↗

Frequency of HPRT mutant lymphocytes in a human control population as determined by the T-cell cloning procedure.Semantic proximity Read ↗

Effect of dietary intake and lifestyle factors on in vivo mutant frequency at the HPRT gene locus in healthy human subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.