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Article

The influence of smoking and diet on the hypoxanthine phosphoribosyltransferase (hprt) mutant frequency in circulating T lymphocytes from a normal human population.

Mutation research - 1 Sept 1995

Duthie S J, Ross M, Collins A R

Abstract excerpt

The influence of the dietary antioxidants vitamin C, alpha- and beta-carotene, lycopene, lutein/zeaxanthin, phytofluene, beta-cryptoxanthin, retinol and alpha- and gamma-tocopherol on the hypoxanthine phosphoribosyltransferase (hprt) mutant frequency in human peripheral T lymphocytes was investig...

Topics

Adult
Antioxidants
Ascorbic Acid
Diet
Humans
Hypoxanthine Phosphoribosyltransferase
Male
Mutation
Smoking
T-Lymphocytes

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7666869
DOI: 10.1016/0027-5107(95)00051-j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7666869-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The influence of smoking and diet on the hypoxanthine phosphoribosyltransferase (hprt) mutant frequency in circulating T lymphocytes from a normal human population.PMID 7666869Read ↗

Factors affecting HPRT mutant frequency in T-lymphocytes of smokers and nonsmokers.Semantic proximity Read ↗

Dietary fruit and vegetables protect against somatic mutation in vivo, but low or high intake of carotenoids does not.Semantic proximity Read ↗

Enhanced hprt mutant frequency but no significant difference in mutation spectrum between a smoking and a non-smoking human population.Semantic proximity Read ↗

Mutational spectra at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in T-lymphocytes of nonsmoking and smoking lung cancer patients.Semantic proximity Read ↗

Influence of smoking and donor age on the spectrum of in vivo mutation at the HPRT-locus in T lymphocytes of healthy adults.Semantic proximity Read ↗

Impact of age and environment on somatic mutation at the hprt gene of T lymphocytes in humans.Semantic proximity Read ↗

Studies on the HPRT mutant frequency in T lymphocytes from healthy Indian male population as a function of age and smoking.Semantic proximity Read ↗

Frequencies of hprt mutant lymphocytes in smokers, non-smokers, and former smokers.Semantic proximity Read ↗

Influence of sex, smoking and age on human hprt mutation frequencies and spectra.Semantic proximity Read ↗

Spectrum of somatic mutation at the hypoxanthine phosphoribosyltransferase (hprt) gene of healthy people.Semantic proximity Read ↗

Frequency of HPRT mutant lymphocytes in a human control population as determined by the T-cell cloning procedure.Semantic proximity Read ↗

Effect of dietary intake and lifestyle factors on in vivo mutant frequency at the HPRT gene locus in healthy human subjects.Semantic proximity Read ↗

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