Article
The kinetochore is an enhancer of pericentric cohesin binding.
PLoS biology - 1 Sept 2004
Weber Stewart A, Gerton Jennifer L, Polancic Joan E, DeRisi Joseph L, Koshland Douglas, Megee Paul C
Abstract excerpt
The recruitment of cohesins to pericentric chromatin in some organisms appears to require heterochromatin associated with repetitive DNA. However, neocentromeres and budding yeast centromeres lack flanking repetitive DNA, indicating that cohesin recruitment occurs through an alternative pathway. Here, we demonstrate that all budding yeast chromosomes assemble cohesin domains that extend over 20-50 kb of unique...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
