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Article

Chromatin assembly factor I and Hir proteins contribute to building functional kinetochores in S. cerevisiae.

Genes & development - 1 Jan 2002

Sharp Judith A, Franco Alexa A, Osley Mary Ann, Kaufman Paul D

Abstract excerpt

Budding yeast centromeres are comprised of approximately 125-bp DNA sequences that direct formation of the kinetochore, a specialized chromatin structure that mediates spindle attachment to chromosomes. We report here a novel role for the histone deposition complex chromatin assembly factor I (CAF-I) in building centromeric chromatin. The contribution of CAF-I to kinetochore function overlaps that of the Hir...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11782447
DOI: 10.1101/gad.925302
PMCID: PMC155315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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