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Article

The yeast RSC chromatin-remodeling complex is required for kinetochore function in chromosome segregation.

Molecular and cellular biology - 1 May 2003

Hsu Jing-Mei, Huang Jian, Meluh Pamela B, Laurent Brehon C

Abstract excerpt

The accurate segregation of chromosomes requires the kinetochore, a complex protein machine that assembles onto centromeric DNA to mediate attachment of replicated sister chromatids to the mitotic spindle apparatus. This study reveals an important role for the yeast RSC ATP-dependent chromatin-remodeling complex at the kinetochore in chromosome transmission. Mutations in genes encoding two core subunits of RSC,...

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Source

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Identifiers

PMID: 12697820
DOI: 10.1128/MCB.23.9.3202-3215.2003
PMCID: PMC153182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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