Article
Analysis of kinesin motor function at budding yeast kinetochores.
The Journal of cell biology - 13 Mar 2006
Tytell Jessica D, Sorger Peter K
Abstract excerpt
Accurate chromosome segregation during mitosis requires biorientation of sister chromatids on the microtubules (MT) of the mitotic spindle. Chromosome-MT binding is mediated by kinetochores, which are multiprotein structures that assemble on centromeric (CEN) DNA. The simple CENs of budding yeast are among the best understood, but the roles of kinesin motor proteins at yeast kinetochores have yet to be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
