Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore.

Cell - 12 Dec 2008

Hori Tetsuya, Amano Miho, Suzuki Aussie, Backer Chelsea B, Welburn Julie P, Dong Yimin, McEwen Bruce F, Shang Wei-Hao, Suzuki Emiko, Okawa Katsuya, Cheeseman Iain M, Fukagawa Tatsuo

Abstract excerpt

Kinetochore specification and assembly requires the targeted deposition of specialized nucleosomes containing the histone H3 variant CENP-A at centromeres. However, CENP-A is not sufficient to drive full-kinetochore assembly, and it is not clear how centromeric chromatin is established. Here, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantigens
Share to Centromere
Share to Chickens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomal Proteins, Non-Histone

Share to HeLa Cells

Share to Histones

Share to Kinetochores

Share to Nucleosomes

Source

Identifiers

PMID: 19070575
DOI: 10.1016/j.cell.2008.10.019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19070575-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore.PMID 19070575Read ↗

Assembly principles and stoichiometry of a complete human kinetochore moduleSemantic proximity Read ↗

The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.Semantic proximity Read ↗

Structure of the human inner kinetochore CCAN complex and its significance for human centromere organizationSemantic proximity Read ↗

Dual recognition of CENP-A nucleosomes is required for centromere assembly.Semantic proximity Read ↗

The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast.Semantic proximity Read ↗

The ratio between centromeric proteins CENP-A and CENP-C maintains homeostasis of human centromeresSemantic proximity Read ↗

CENP-A and CENP-B collaborate to create an open centromeric chromatin stateSemantic proximity Read ↗

Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosomeSemantic proximity Read ↗

Polo kinase recruitment via the constitutive centromere-associated network at the kinetochore elevates centromeric RNA.Semantic proximity Read ↗

Stepwise unfolding supports a subunit model for vertebrate kinetochores.Semantic proximity Read ↗

CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold.Semantic proximity Read ↗

CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.