Article
The FU gene and its possible protein isoforms.
BMC genomics - 22 Jul 2004
Østerlund Torben, Everman David B, Betz Regina C, Mosca Monica, Nöthen Markus M, Schwartz Charles E, Zaphiropoulos Peter G, Toftgård Rune
Abstract excerpt
BACKGROUND: FU is the human homologue of the Drosophila gene fused whose product fused is a positive regulator of the transcription factor Cubitus interruptus (Ci). Thus, FU may act as a regulator of the human counterparts of Ci, the GLI transcription factors. Since Ci and GLI are targets of Hedgehog signaling in development and morphogenesis, it is expected that FU plays an important role in Sonic, Desert and/or...
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