Article
Over-expression of a novel nuclear interactor of Suppressor of fused, the Drosophila myelodysplasia/myeloid leukaemia factor, induces abnormal morphogenesis associated with increased apoptosis and DNA synthesis.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 2003
Fouix Sylvaine, Martin-Lannerée Séverine, Sanial Matthieu, Morla Luciana, Lamour-Isnard Claudie, Plessis Anne
Abstract excerpt
BACKGROUND: In Drosophila and vertebrates, suppressor of fused (Su(fu)) proteins act as negative regulators of the Gli/Ci transcription factors, which mediate the transcriptional effects of Hh signalling. RESULTS: We sought for novel partners of Su(fu) in fly using the two-hybrid method. Most of...
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