Article
Genotoxicity of acrylamide and glycidamide.
Journal of the National Cancer Institute - 7 Jul 2004
Besaratinia Ahmad, Pfeifer Gerd P
Abstract excerpt
BACKGROUND: Acrylamide, a known rodent carcinogen, is found in the human diet. However, the mechanism by which acrylamide exerts its carcinogenic effects remains unclear. METHODS: Normal human bronchial epithelial cells and Big Blue mouse embryonic fibroblasts that carry a lambda phage cII transg...
Topics
- Acrylamide
- Adenine
- Animals
- Cell Culture Techniques
- Cytosine
- DNA Adducts
- Dose-Response Relationship, Drug
- Epoxy Compounds
- Fibroblasts
- Guanine
- Humans
- Mice
- Mutagens
