Article
Experimental analysis of exome-scale mutational signature of glycidamide, the reactive metabolite of acrylamide
2018-01-27
Abstract excerpt
Acrylamide, a probable human carcinogen, is ubiquitously present in the human environment, with sources including heated starchy foods, coffee and cigarette smoke. Humans are also exposed to acrylamide occupationally. Acrylamide is genotoxic, inducing gene mutations and chromosomal aberrations in various experimental settings. Covalent haemoglobin adducts were reported in acrylamide-exposed humans and DNA adducts...
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Identifiers and source
- Literature Corpus work
- 635070e7-a1df-5028-8ca8-8dd0a63875d8
- DOI
- 10.1101/254664