Article
Evaluation of cII gene mutation in the brains of Big Blue mice exposed to acrylamide and glycidamide in drinking water.
The Journal of toxicological sciences - 1 Jan 2016
Li Hai-Fang, Shelton Sharon D, Townsend Todd A, Mei Nan, Manjanatha Mugimane G
Abstract excerpt
Potential health risks for humans from dietary exposure to acrylamide (AA) and its reactive epoxide metabolite, glycidamide (GA), exist because substantial amounts of AA are found in a variety of fried and baked starchy foods. AA is tumorigenic in rodents, and a large number of studies indicate that AA is genotoxic in multiple organs of mice and rats. Although AA is neurotoxic, there are no reports on AA-induced...
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