Timing and checkpoints in the regulation of mitotic progression.

doi:10.1016/j.devcel.2004.06.006

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Article

Timing and checkpoints in the regulation of mitotic progression.

Developmental cell - 1 Jul 2004

Meraldi Patrick, Draviam Viji M, Sorger Peter K

Abstract excerpt

Accurate chromosome segregation relies on the precise regulation of mitotic progression. Regulation involves control over the timing of mitosis and a spindle assembly checkpoint that links anaphase onset to the completion of chromosome-microtubule attachment. In this paper, we combine live-cell i...

Topics

Anaphase
Carrier Proteins
Cell Cycle Proteins
Cytoskeletal Proteins
Cytosol
Genes, cdc
HeLa Cells
Humans
Kinetochores
Microtubules
Mitosis
Nuclear Proteins
Phenotype
Phosphoproteins
Protein Kinases
Protein Serine-Threonine Kinases
RNA Interference
Repressor Proteins

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