Article
Spatial regulation of the spindle assembly checkpoint and anaphase-promoting complex in Aspergillus nidulans.
Molecular microbiology - 1 Feb 2015
Edgerton Heather, Paolillo Vitoria, Oakley Berl R
Abstract excerpt
The spindle assembly checkpoint (SAC) plays a critical role in preventing mitotic errors by inhibiting anaphase until all kinetochores are correctly attached to spindle microtubules. In spite of the economic and medical importance of filamentous fungi, relatively little is known about the behavior of SAC proteins in these organisms. In our efforts to understand the role of γ-tubulin in cell cycle regulation, we...
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