A spindle checkpoint functions during mitosis in the early Caenorhabditis elegans embryo.

doi:10.1091/mbc.e04-08-0712

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Article

A spindle checkpoint functions during mitosis in the early Caenorhabditis elegans embryo.

Molecular biology of the cell - 1 Mar 2005

Encalada Sandra E, Willis John, Lyczak Rebecca, Bowerman Bruce

Abstract excerpt

During mitosis, chromosome segregation is regulated by a spindle checkpoint mechanism. This checkpoint delays anaphase until all kinetochores are captured by microtubules from both spindle poles, chromosomes congress to the metaphase plate, and the tension between kinetochores and their attached...

Topics

Alleles
Anaphase
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Chromosomal Proteins, Non-Histone
Chromosomes
Cloning, Molecular
Embryo, Nonmammalian
Gene Expression Regulation, Developmental
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kinesins

Kinetochores

Mitosis

Models, Biological

Models, Genetic

Nocodazole

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 15616189
DOI: 10.1091/mbc.e04-08-0712
PMCID: PMC551473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15616189-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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A spindle checkpoint functions during mitosis in the early Caenorhabditis elegans embryo.PMID 15616189Read ↗

Components of the spindle-assembly checkpoint are essential in Caenorhabditis elegans.Semantic proximity Read ↗

Spindle assembly checkpoint strength is linked to cell fate in theCaenorhabditis elegansembryoSemantic proximity Read ↗

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Mutual antagonism between the anaphase promoting complex and the spindle assembly checkpoint contributes to mitotic timing in Caenorhabditis elegans.Semantic proximity Read ↗

Spindle assembly checkpoint genes reveal distinct as well as overlapping expression that implicates MDF-2/Mad2 in postembryonic seam cell proliferation in Caenorhabditis elegans.Semantic proximity Read ↗

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