Article
A spindle checkpoint functions during mitosis in the early Caenorhabditis elegans embryo.
Molecular biology of the cell - 1 Mar 2005
Encalada Sandra E, Willis John, Lyczak Rebecca, Bowerman Bruce
Abstract excerpt
During mitosis, chromosome segregation is regulated by a spindle checkpoint mechanism. This checkpoint delays anaphase until all kinetochores are captured by microtubules from both spindle poles, chromosomes congress to the metaphase plate, and the tension between kinetochores and their attached microtubules is properly sensed. Although the spindle checkpoint can be activated in many different cell types, the...
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