Article

Cyclin A/Cdk1 promotes chromosome alignment and timely mitotic progression

2023-12-21

Abstract excerpt

<h4>ABSTRACT</h4> To ensure genomic fidelity a series of spatially and temporally coordinated events are executed during prometaphase of mitosis, including bipolar spindle formation, chromosome attachment to spindle microtubules at kinetochores, the correction of erroneous kinetochore-microtubule (k-MT) attachments, and chromosome congression to the spindle equator. Cyclin A/Cdk1 kinase plays a key role in destab...

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Literature Corpus work: 32752f77-3fbb-50ee-9d80-6cd3a6f323c5
DOI: 10.1101/2023.12.21.572788

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