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Article

The impact of population heterogeneity on risk estimation in genetic counseling.

BMC medical genetics - 30 Jun 2004

Liu Wenlei, Icitovic Nikolina, Shaffer Michele L, Chase Gary A

Abstract excerpt

BACKGROUND: Genetic counseling has been an important tool for evaluating and communicating disease susceptibility for decades, and it has been applied to predict risks for a wide class of hereditary disorders. Most diseases are complex in nature and are affected by multiple genes and environmental conditions; it is highly likely that DNA tests alone do not define all the genetic factors responsible for a disease,...

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Identifiers

PMID: 15228628
DOI: 10.1186/1471-2350-5-18
PMCID: PMC449710

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Source receipt: pubmed, retrieved 7 Sept 2026.

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