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Article

Construction of endophenotypes for complex diseases in the presence of heterogeneity.

BMC genetics - 30 Dec 2005

Chen Chien-Hsiun, Kuo Chih-Ling, Lin Michael C P, Liang Yu-Jen, Fann Cathy S J

Abstract excerpt

Endophenotypes such as behavior disorders have been increasingly adopted in genetic studies for complex traits. For efficient gene mapping, it is essential that an endophenotype is associated with the disease of interest and is inheritable or co-segregating within families. In this study, we proposed a strategy to construct endophenotypes to analyze the Genetic Analysis Workshop 14 simulated dataset. Initially,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16451598
DOI: 10.1186/1471-2156-6-S1-S139
PMCID: PMC1866797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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