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Article

Linkage analysis of quantitative trait loci in the presence of heterogeneity.

Human heredity - 1 Jan 2003

Ekstrøm Claus Thorn, Dalgaard Peter

Abstract excerpt

Variance component modeling for linkage analysis of quantitative traits is a powerful tool for detecting and locating genes affecting a trait of interest, but the presence of genetic heterogeneity will decrease the power of a linkage study and may even give biased estimates of the location of the quantitative trait loci. Many complex diseases are believed to be influenced by multiple genes and therefore genetic...

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Identifiers

PMID: 12890922
DOI: 10.1159/000071806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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