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Article

Genetic variants influencing phenotypic variance heterogeneity.

Human molecular genetics - 1 Mar 2018

Ek Weronica E, Rask-Andersen Mathias, Karlsson Torgny, Enroth Stefan, Gyllensten Ulf, Johansson Åsa

Abstract excerpt

Most genetic studies identify genetic variants associated with disease risk or with the mean value of a quantitative trait. More rarely, genetic variants associated with variance heterogeneity are considered. In this study, we have identified such variance single-nucleotide polymorphisms (vSNPs) and examined if these represent biological gene × gene or gene × environment interactions or statistical artifacts...

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PMID: 29325024
DOI: 10.1093/hmg/ddx441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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