Article
Apolipoprotein E epsilon4 allele differently affects the patterns of neuropsychological presentation in early- and late-onset Alzheimer's disease patients.
Dementia and geriatric cognitive disorders - 1 Jan 2004
Marra Camillo, Bizzarro Alessandra, Daniele Antonio, De Luca Lara, Ferraccioli Monica, Valenza Alessandro, Brahe Christina, Tiziano Francesco Danilo, Gainotti Guido, Masullo Carlo
Abstract excerpt
The presence of the apolipoprotein E (APOE) epsilon4 allele is a definite risk factor for the onset of Alzheimer's disease (AD). Its presence seems to affect especially the memory in the early stage of the disease, but the effect on the progression of the disease and survival is still controversial. Some longitudinal studies could be influenced by variables other than APOE, such as the response to medical...
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