Article
Preclinical memory profile in Alzheimer patients with and without allele APOE-epsilon4.
European neurology - 1 Jan 2004
Estévez-González Armando, García-Sánchez Carmen, Boltes Anunciación, Otermín Pilar, Baiget Montserrat, Escartín Antonio, del Rio Elisabeth, Gironell Alex, Kulisevsky Jaime
Abstract excerpt
To investigate the association between APOE-epsilon4 allele and memory phenotype in the preclinical stage of Alzheimer's disease (AD). We compared an extensive preclinical memory profile at the baseline evaluation of 2 AD genotype groups: APOE-epsilon4 allele carriers and patients with APOE-epsilon3 homozygosity. Baseline memory performance was carried out at least 2 years (interval of 27.7 +/- 4 months) before...
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