Article
Apolipoprotein E type 4 allele and Alzheimer's disease: effect on age at onset and relative risk in different age groups.
Journal of neurology - 1 Jun 1996
Kurz A, Altland K, Lautenschlager N, Zimmer R, Busch R, Gerundt I, Lauter H, Müller U
Abstract excerpt
The effect of the apolipoprotein E (apoE) genotype on the age at onset of Alzheimer's disease (AD) and the relative risk conferred by the apoE epsilon 4 allele were studied in 91 patients and 69 healthy age-matched controls. According to the age of presentation, which varied from 44 to 95 years, subjects were divided into four groups. The inheritance of at least one epsilon 4 allele was associated with a...
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