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Article

[Dementia and cognitive impairment pattern: its association with epsilon4 allele of apolipoprotein E gene].

Revista de neurologia - 1 Jan 2000

Rosich-Estragó M, Figuera-Terré L, Mulet-Pérez B, Arrufat-Cardús M T, Pascual San Emeterio A, Arbeola-Rigau I, Labad-Alquézar A, Vilella-Cuadrada E

Abstract excerpt

INTRODUCTION: The APOE epsilon4 allele is a well-established risk factor for Alzheimer's disease. This disease is characterized by a typical progressive cognitive impairment pattern, different from that of other primary dementias such as dementia with Lewy bodies or frontotemporal and vascular dementias, for which there are no conclusive results on the influence of the APOE genotype. OBJECTIVE: Our aim is to...

Topics

Age of Onset
Aged
Aging
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Cognition Disorders
Dementia
Female
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Risk Factors

Source

Identifiers

PMID: 15152345

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15152345-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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