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Article

Serotonin transporter polymorphism related to amygdala excitability and symptom severity in patients with social phobia.

Neuroscience letters - 27 May 2004

Furmark Tomas, Tillfors Maria, Garpenstrand Håkan, Marteinsdottir Ina, Långström Bengt, Oreland Lars, Fredrikson Mats

Abstract excerpt

A functional polymorphism in the promoter region of the human serotonin transporter (5-HTT) gene has been related to negative affect and amygdala activity. We studied amygdala activation during social anxiety provocation in relation to affective ratings and 5-HTT genetic variation. [H2(15)O]positron emission tomography was used to estimate amygdala blood flow during private and public speaking (baseline and...

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Source

Identifiers

PMID: 15158011
DOI: 10.1016/j.neulet.2004.02.070

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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