Neural and behavioral responses to threatening emotion faces in children as a function of the short allele of the serotonin transporter gene.

doi:10.1016/j.biopsycho.2010.04.009

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Article

Neural and behavioral responses to threatening emotion faces in children as a function of the short allele of the serotonin transporter gene.

Biological psychology - 1 Sept 2010

Thomason Moriah E, Henry Melissa L, Paul Hamilton J, Joormann Jutta, Pine Daniel S, Ernst Monique, Goldman David, Mogg Karin, Bradley Brendan P, Britton Jennifer C, Lindstrom Kara M, Monk Christopher S, Sankin Lindsey S, Louro Hugo M C, Gotlib Ian H

Abstract excerpt

Recent evidence suggests that a genetic polymorphism in the promoter region (5-HTTLPR) of the serotonin transporter gene (SLC6A4) mediates stress reactivity in adults. Little is known, however, about this gene-brain association in childhood and adolescence, generally conceptualized as a time of heightened stress reactivity. The present study examines the association between 5-HTTLPR allelic variation and...

Topics

Adolescent
Analysis of Variance
Attention
Brain
Brain Mapping
Child
Emotions
Face
Fear
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Frequency

Genome-Wide Association Study

Genotype

Humans

Image Processing, Computer-Assisted

Magnetic Resonance Imaging

Male

Oxygen

Source

Open in PubMed Open full text

Identifiers

PMID: 20493234
DOI: 10.1016/j.biopsycho.2010.04.009
PMCID: PMC2914171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20493234-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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