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Article

Serotonin transporter genotype modulates the association between depressive symptoms and amygdala activity among psychiatrically healthy adults.

Psychiatry research - 30 Sept 2011

Gillihan Seth J, Rao Hengyi, Brennan Lauretta, Wang Danny J J, Detre John A, Sankoorikal Geena Mary V, Brodkin Edward S, Farah Martha J

Abstract excerpt

Recent attempts to understand the biological bases of depression vulnerability have revealed that both the short allele of the serotonin transporter-linked polymorphic region (5-HTTLPR) and activity in the amygdala are associated with depression. Other studies have reported amygdala hyperactivity associated with the 5-HTTLPR short allele, linking the genetic and neuroimaging lines of research and suggesting a...

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Identifiers

PMID: 21764567
DOI: 10.1016/j.pscychresns.2011.03.003
PMCID: PMC3156965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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