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Article

A susceptibility gene for affective disorders and the response of the human amygdala.

Archives of general psychiatry - 1 Feb 2005

Hariri Ahmad R, Drabant Emily M, Munoz Karen E, Kolachana Bhaskar S, Mattay Venkata S, Egan Michael F, Weinberger Daniel R

Abstract excerpt

BACKGROUND: A common regulatory variant (5-HTTLPR) in the human serotonin transporter gene (SLC6A4), resulting in altered transcription and transporter availability, has been associated with vulnerability for affective disorders, including anxiety and depression. A recent functional magnetic resonance imaging study suggested that this association may be mediated by 5-HTTLPR effects on the response bias of the...

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PMID: 15699291
DOI: 10.1001/archpsyc.62.2.146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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