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Article

Genetic polymorphisms in monoamine systems and outcome of cognitive behavior therapy for social anxiety disorder.

PloS one - 1 Jan 2013

Andersson Evelyn, Rück Christian, Lavebratt Catharina, Hedman Erik, Schalling Martin, Lindefors Nils, Eriksson Elias, Carlbring Per, Andersson Gerhard, Furmark Tomas

Abstract excerpt

OBJECTIVE: The role of genetics for predicting the response to cognitive behavior therapy (CBT) for social anxiety disorder (SAD) has only been studied in one previous investigation. The serotonin transporter (5-HTTLPR), the catechol-o-methyltransferase (COMT) val158met, and the tryptophan hydroxylase-2 (TPH2) G-703T polymorphisms are implicated in the regulation of amygdala reactivity and fear extinction and...

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Source

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Identifiers

PMID: 24260145
DOI: 10.1371/journal.pone.0079015
PMCID: PMC3829855

Genes

TPH2
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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