Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of the E-cadherin/catenin complex in colorectal carcinoma cell lines.

International journal of experimental pathology - 1 Apr 2004

El-Bahrawy Mona, Poulsom Richard, Rowan Andrew J, Tomlinson Ian T M, Alison Malcolm R, Poulsom S Richard, Tomlinson Ian T

Abstract excerpt

The E-cadherin/catenin complex is a prime mediator of cell-cell adhesion. APC mutations can result in loss of beta-catenin downregulation and an accumulation of beta-catenin in the cell. Beta-CATENIN mutations can have a similar effect. The aim of this study was to investigate the effect of beta-CATENIN and APC mutations on the expression and assembly of the E-cadherin/catenin complex. Five colorectal carcinoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to beta Catenin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cadherins

Share to Cell Adhesion

Share to Cytoskeletal Proteins

Share to Genes, APC

Share to Precipitin Tests

Share to Trans-Activators

Source

Open in PubMed Open full text

Identifiers

PMID: 15154912
DOI: 10.1111/j.0959-9673.2004.0371.x
PMCID: PMC2517458

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of the E-cadherin/catenin complex in colorectal carcinoma cell lines.PMID 15154912Read ↗

The role of the E-cadherin/catenin complex in gastrointestinal cancer.Semantic proximity Read ↗

E-cadherin-catenin cell-cell adhesion complex and human cancer.Semantic proximity Read ↗

The role of E-cadherin-catenin complex: more than an intercellular glue?Semantic proximity Read ↗

Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas.Semantic proximity Read ↗

A truncated beta-catenin disrupts the interaction between E-cadherin and alpha-catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines.Semantic proximity Read ↗

Erbb Receptors and Epithelial-Cadherin–Catenin Complex In Human CarcinomasSemantic proximity Read ↗

Cadherin and catenin alterations in human cancer.Semantic proximity Read ↗

The interactions of APC, E-cadherin and beta-catenin in tumour development and progression.Semantic proximity Read ↗

Expression of alpha-catenin in alpha-catenin-deficient cells results in a reduced proliferation in three-dimensional multicellular spheroids but not in two-dimensional monolayer cultures.Semantic proximity Read ↗

Expression of the E-cadherin-catenin complex in lung neuroendocrine tumours.Semantic proximity Read ↗

Level of α-catenin expression in colorectal cancer correlates with invasiveness, metastatic potential, and survivalSemantic proximity Read ↗

E-cadherin complex and its abnormalities in human breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.