Article
The role of E-cadherin-catenin complex: more than an intercellular glue?
Annals of surgical oncology - 1 Dec 2000
Harrington K J, Syrigos K N, Harington K J
Abstract excerpt
It is now widely recognized that alterations in the adhesion properties of neoplastic cells may play a pivotal role in the development and progression of the malignant phenotype in a range of tumor types. The cadherins and catenins, being the prime mediators of cell-cell adhesion, are intimately involved in the control of morphological differentiation and cellular proliferation; loss of their intercellular...
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