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Article

Level of α-catenin expression in colorectal cancer correlates with invasiveness, metastatic potential, and survival

1 Jun 1998

Abstract excerpt

BACKGROUND AND OBJECTIVES: Decreased expression of the E-cadherin/alpha-catenin cell-cell adhesion complex is considered to elicit detachment of tumor cells from primary lesions and development of metastases. The immunohistochemical profile of alpha-catenin in colorectal cancer, as well as its correlation with differentiation, lymph node/liver metastasis and patient survival is presented in this study. METHODS:...

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PMID: 9624037
DOI: 10.1002/(sici)1096-9098(199806)68:2<92::aid-jso4>3.0.co;2-f

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