Article
E-cadherin-catenin cell-cell adhesion complex and human cancer.
The British journal of surgery - 1 Aug 2000
Wijnhoven B P, Dinjens W N, Pignatelli M
Abstract excerpt
BACKGROUND: The E-cadherin-catenin complex plays a crucial role in epithelial cell-cell adhesion and in the maintenance of tissue architecture. Perturbation in the expression or function of this complex results in loss of intercellular adhesion, with possible consequent cell transformation and tumour progression. Recently, much progress has been made in understanding the interaction between the different...
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