Article
E-cadherin complex and its abnormalities in human breast cancer.
Surgical oncology - 1 Dec 2000
Jiang W G, Mansel R E
Abstract excerpt
E-cadherin and its adhesion complex play an essential role in the adhesion of breast cancer cells and tissues. Members of the complex, such as beta-catenin, act as regulators on cell adhesion, and are involved in cell signalling and transcription regulation. The adhesion complex is a known structure in the control of tumour progression and metastasis. Recent years have seen a rapid expansion in the understanding...
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