Article
Expression of the E-cadherin-catenin complex in lung neuroendocrine tumours.
The Journal of pathology - 1 May 2001
Clavel C E, Nollet F, Berx G, Tejpar S, Nawrocki-Raby B, Kaplan H H, van Roy F M, Birembaut P L
Abstract excerpt
Neuroendocrine tumours (NETs) of the lung represent a wide spectrum of phenotypically distinct entities, with differences in tumour progression and aggressiveness. The redistribution and/or the loss of various cell adhesion molecules, such as the E-cadherin-catenin complex, play a predominant role in carcinogenesis and in tumour invasion. Moreover, mutations in exon 3 of the beta-catenin gene, the adenomatous...
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