Erbb Receptors and Epithelial-Cadherin–Catenin Complex In Human Carcinomas

doi:10.2217/14796694.2.6.765

Article

Erbb Receptors and Epithelial-Cadherin–Catenin Complex In Human Carcinomas

8 Dec 2006

Abstract excerpt

The ErbB family of receptor tyrosine kinases have important roles in maintaining normal epithelial cell function. The ErbBs are involved in the interaction between cells and cell-matrix adhesion molecules and have proven critical in maintaining the integrity of the epithelial cell environment. Deregulation of these tyrosine receptors has been associated with several human diseases. In particular, the expression...

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