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Article

Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay.

European journal of pharmacology - 3 May 2004

Saraiva Lucília, Fresco Paula, Pinto Eugénia, Gonçalves Jorge

Abstract excerpt

An alternative in vivo assay, based on growth inhibition of yeast expressing an individual mammalian protein kinase C (PKC) isoform (proportional to the degree of PKC activation), was used to characterize the activities of phorbol-12-myristate-13-acetate (PMA) and its analogues on classical (alpha and betaI), novel (delta and eta) and atypical (zeta) PKC isoforms. Effects of PMA, 4alpha-PMA,...

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PMID: 15140626
DOI: 10.1016/j.ejphar.2004.03.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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