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Article

PKC epsilon has an alcohol-binding site in its second cysteine-rich regulatory domain.

The Biochemical journal - 15 Jul 2009

Das Joydip, Pany Satyabrata, Rahman Ghazi M, Slater Simon J

Abstract excerpt

Alcohols regulate the expression and function of PKC (protein kinase C), and it has been proposed that an alcohol-binding site is present in PKC alpha in its C1 domain, which consists of two cysteine-rich subdomains, C1A and C1B. A PKC epsilon-knockout mouse showed a significant decrease in alcohol consumption compared with the wild-type. The aim of the present study was to investigate whether an alcohol-binding...

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Identifiers

PMID: 19432558
DOI: 10.1042/BJ20082271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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