Article
Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta.
The Journal of biological chemistry - 25 Sept 1993
Mischak H, Pierce J H, Goodnight J, Kazanietz M G, Blumberg P M, Mushinski J F
Abstract excerpt
It is generally accepted that the multiple, similar protein kinase C (PKC) isozymes are responsible for different specialized physiological processes, but evidence that directly assigns specific functions to specific isozymes is scarce. To test whether specific PKC isozymes are involved in myeloi...
Topics
- Animals
- Blotting, Western
- Cell Differentiation
- Cell Line
- Electrophoresis, Polyacrylamide Gel
- Isoenzymes
- Kinetics
- Macrophages
- Mice
- Phenotype
- Protein Kinase C
- Recombinant Proteins
- Stem Cells
- Tetradecanoylphorbol Acetate
- Time Factors
- Transfection