Article
Structural and functional diversities of a family of signal transducing protein kinases, protein kinase C family; two distinct classes of PKC, conventional cPKC and novel nPKC.
Advances in enzyme regulation - 1 Jan 1991
Ohno S, Akita Y, Hata A, Osada S, Kubo K, Konno Y, Akimoto K, Mizuno K, Saido T, Kuroki T
Abstract excerpt
Recent molecular cloning and biochemical experiments on the nature of protein kinase C (PKC) have revealed the existence of two distinct classes of phorbol ester (and diacylglycerol) receptor/protein kinase, conventional PKC (cPKC) and novel PKC (nPKC). Each of these classes contains multiple related molecules expressed in tissues and cells in a type-specific manner. Although nPKC does not show the typical PKC...
Topics
- Animals
- Biological Evolution
- Cloning, Molecular
- Genetic Variation
- Multigene Family
- Protein Kinase C
- Signal Transduction