Article
Two single nucleotide polymorphisms in the CYP17 and COMT Genes--relation to bone mass and longitudinal bone changes in postmenopausal women with or without hormone replacement therapy. The Danish Osteoporosis Prevention Study.
Calcified tissue international - 1 Aug 2004
Tofteng C L, Abrahamsen B, Jensen J E B, Petersen S, Teilmann J, Kindmark A, Vestergaard P, Gram J, Langdahl B L, Mosekilde L
Abstract excerpt
Sex steroids are important physiologic regulators of bone mass, and genes regulating sex steroid production and metabolism are obvious as candidate genes for osteoporosis susceptibility. We present data from a study of 1795 recent postmenopausal women, assigned to either hormone replacement therapy (HRT) or no treatment and followed for 5 years. The association between bone mass measurements and two single...
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